A genome-wide study of preferential amplification/hybridization in microarray-based pooled DNA experiments
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چکیده
منابع مشابه
A genome-wide study of preferential amplification/hybridization in microarray-based pooled DNA experiments
Microarray-based pooled DNA methods overcome the cost bottleneck of simultaneously genotyping more than 100 000 markers for numerous study individuals. The success of such methods relies on the proper adjustment of preferential amplification/hybridization to ensure accurate and reliable allele frequency estimation. We performed a hybridization-based genome-wide single nucleotide polymorphisms (...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2006
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkl446